Patients suffering from depression are often treated with a variety of antidepressants. A side effect associated with many of these antidepressants is
suicidal tendencies. As a result of this, the FDA requires the medications to bear a "Black Box" Warning. In this discussion, you will read about "Black Box"
warnings, discuss the condition of depression, the adverse effects of antidepressants, and adjunct therapies.
• Explain the use and side effects of prescription and non-prescription medications, and alternative therapies (e.g., herbal products, dietary
supplements, homeopathy, lifestyle modification) used to treat common disease states, including those that affect the following body systems:
musculoskeletal, nervous, gastrointestinal, renal and endocrine. (ASHP Objective 11.2)
Step 1: Read the following articles about Black Box Warnings
& FDA Adverse.pdf
Pay close attention to the drug names and classifications listed as having a Black Box Warning. Which of the drugs listed treat Nervous System disorders?
Step 2: Respond to the following:
Many different types of drugs can have a Black Box warning for many reasons. There are however, a number of drugs used to treat Nervous System
disorders, including depression, that carry these warnings. After reading the article on Black Box warnings:
Would the presence of a Black Box warning on and antidepressant affect your decision to use this type of therapy or treatment? Why or why not?
• What other therapies can be utilized in the treatment of depression?
• Do you feel these other therapies are effective? Why or why not?
• What is your role as a Pharmacy Technician when a patient is filling these types of prescriptions?